Structural and population characterization of MrkD, the adhesive subunit of type 3 fimbriae.

doi:10.1128/JB.00753-13

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Article

Structural and population characterization of MrkD, the adhesive subunit of type 3 fimbriae.

Journal of bacteriology - 1 Dec 2013

Stahlhut Steen G, Chattopadhyay Sujay, Kisiela Dagmara I, Hvidtfeldt Kristian, Clegg Steven, Struve Carsten, Sokurenko Evgeni V, Krogfelt Karen A

Abstract excerpt

Type 3 fimbriae are adhesive organelles found in enterobacterial pathogens. The fimbriae promote biofilm formation on biotic and abiotic surfaces; however, the exact identity of the receptor for the type 3 fimbriae adhesin, MrkD, remains elusive. We analyzed naturally occurring structural and functional variabilities of the MrkD adhesin from Klebsiella pneumoniae and Escherichia coli isolates of diverse origins....

Topics

Adhesins, Bacterial
Adhesins, Escherichia coli
Alleles
Bacterial Adhesion
Biofilms
DNA, Bacterial
Escherichia coli
Escherichia coli Proteins
Fimbriae Proteins
Genetic Variation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Klebsiella pneumoniae

Microbial Interactions

Models, Molecular

Molecular Sequence Data

Mutation, Missense

Protein Conformation

Protein Structure, Tertiary

Saccharomyces cerevisiae

Source

Open in PubMed Open full text

Identifiers

PMID: 24123820
DOI: 10.1128/JB.00753-13
PMCID: PMC3889607

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