Article
A genome-wide association study of severe teenage acne in European Americans.
Human genetics - 1 Mar 2014
Zhang Mingfeng, Qureshi Abrar A, Hunter David J, Han Jiali
Abstract excerpt
Despite the family aggregation of severe teenage acne, the genetic basis of this common skin condition remains unclear. We conducted a genome-wide association study (GWAS) on severe teenage acne in 928 European Americans. The SNP rs4133274 on chromosome 8q24 (72 kb upstream of MYC) revealed the most significant association with severe teenage acne (p value = 1.7 × 10(-6)). The variant allele of this SNP (G...
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