Article
Heritability and GWAS Analyses of Acne in Australian Adolescent Twins.
Twin research and human genetics : the official journal of the International Society for Twin Studies - 1 Dec 2017
Mina-Vargas Angela, Colodro-Conde Lucía, Grasby Katrina, Zhu Gu, Gordon Scott, Medland Sarah E, Martin Nicholas G
Abstract excerpt
Acne vulgaris is a skin disease with a multifactorial and complex pathology. While several twin studies have estimated that acne has a heritability of up to 80%, the genomic elements responsible for the origin and pathology of acne are still undiscovered. Here we performed a twin-based structural equation model, using available data on acne severity for an Australian sample of 4,491 twins and their siblings aged...
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