Article
Two new susceptibility loci 1q24.2 and 11p11.2 confer risk to severe acne.
Nature communications - 1 Jan 2014
He Li, Wu Wen-Juan, Yang Jian-Kang, Cheng Hui, Zuo Xian-Bo, Lai Wei, Gao Tian-Wen, Ma Cui-Lin, Luo Na, Huang Jian-Qing, Lu Feng-Yan, Liu Ye-Qiang, Huang Yi-Jin, Lu Qian-Jin, Zhang Huai-Liang, Wang Lin, Wang Wei-Zhen, Wang Mei-Mei, Xiao Sheng-Xiang, Sun Qing, Li Chun-Yang, Bai Yan-Ping, Li Hui, Zhou Zhan-Chao, Zhou Fu-Sheng, Chen Gang, Liang Bo, Qi Jue, Yang Xiao-Yan, Yang Ting, Zheng Xing, Sun Liang-Dan, Zhang Xue-Jun, Zhang Ya-Ping
Abstract excerpt
Severe acne is a chronic inflammatory skin disorder characterized by widespread inflammatory lesions including nodules, cysts and potential scarring. Here we perform the first genome-wide association study of severe acne in a Chinese Han population comprising 1,056 cases and 1,056 controls using the Illumina HumanOmniZhongHua-8 BeadChip. In an independent cohort of 1,860 cases and 3,660 controls of Chinese Han,...
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