Article
MLST of housekeeping genes captures geographic population structure and suggests a European origin of Borrelia burgdorferi.
Proceedings of the National Academy of Sciences of the United States of America - 24 Jun 2008
Margos Gabriele, Gatewood Anne G, Aanensen David M, Hanincová Klára, Terekhova Darya, Vollmer Stephanie A, Cornet Muriel, Piesman Joseph, Donaghy Michael, Bormane Antra, Hurn Merrilee A, Feil Edward J, Fish Durland, Casjens Sherwood, Wormser Gary P, Schwartz Ira, Kurtenbach Klaus
Abstract excerpt
Lyme borreliosis, caused by the tick-borne bacterium Borrelia burgdorferi, has become the most common vector-borne disease in North America over the last three decades. To understand the dynamics of the epizootic spread and to predict the evolutionary trajectories of B. burgdorferi, accurate information on the population structure and the evolutionary relationships of the pathogen is crucial. We, therefore,...
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