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Article

Prognostic significance of E-cadherin and N-cadherin expression in Gliomas

29 Aug 2017

Abstract excerpt

BACKGROUND: Epithelial-mesenchymal transition (EMT), principally involving an E-cadherin to N-cadherin shift, linked to tumor invasion or metastasis, and therapeutic resistance in various human cancer. A growing body of recent evidence has supported the hypothesis that EMT play a crucial role in the invasive phenotype of gliomas. To evaluate the prognostic connotation of EMT traits in glioma, expression of...

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PMID: 28851312
DOI: 10.1186/s12885-017-3591-z

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