Article
Committed mast cell progenitors in mouse blood differ in maturity between Th1 and Th2 strains.
Allergy - 1 Oct 2013
Dahlin J S, Heyman B, Hallgren J
Abstract excerpt
Mast cell progenitors (MCp) leave the bone marrow and migrate to peripheral tissues where they mature. Although the existence of committed MCp in adult mouse and human blood has been postulated, they have never been found. We have isolated a rare population of cells in adult mouse blood, committed to the mast cell lineage. These were identified as lineage- c-kit(hi) ST2+ integrin β7(hi) CD16/32(hi) cells....
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