Article
Short communication: HIV type 1 tropism determination in a novel dried blood spot membrane and the use of a mixture of outer nested polymerase chain reaction primers.
AIDS research and human retroviruses - 1 Feb 2014
Lavigne Shirlene, Santos Carlos, Arif Muhammad Shoaib, Reis Alexanda, Samer Sadia, Dos Santos Cintia Vilhena, Diaz Ricardo Sobhie
Abstract excerpt
Genotropism was determined in 608 Brazilian samples collected in dried blood spots using Polyethersulfone collection cards. Patients were infected by subtype B (88.8%), F (5.6%), C (3.3%), A (1.8%), and G (0.5%). All patients were exposed to three classes of antiretrovirals, and 59.8% of the samples harbored R5 viruses, 35% non-R5-tropic viruses, and 5.1% harbored mixtures of R5 and non-R5-tropic viruses, with...
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