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Article

Gsp mutation in acromegaly and its influence on TRH-induced paradoxical GH response.

Clinical endocrinology - 1 May 2014

Goto Yuko, Kinoshita Manabu, Oshino Satoru, Arita Hideyuki, Kitamura Tetsuhiro, Otsuki Michio, Shimomura Iichiro, Yoshimine Toshiki, Saitoh Youichi

Abstract excerpt

OBJECTIVE: We recently reported that paradoxical GH response to TRH administration reflects biological characteristics in patients with acromegaly. The aim of this study is to elucidate the relationship between gsp mutations and the paradoxical GH response to TRH. PATIENTS: Sixty-seven patients with acromegaly were included for analysis. Paradoxical increase in serum GH level to TRH, GH suppression by octreotide...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24111551
DOI: 10.1111/cen.12336

Genes

TRH

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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