Article
Polymorphisms in the MT-ATP6 and MT-CYB genes in in vitro fertilization failure.
Mitochondrial DNA - 1 Feb 2015
Mao Gen-Hong, Wang Ya-Nan, Xu Min, Wang Wu-Liang, Tan Li, Tao Shi-Bo
Abstract excerpt
The purpose of this study was to investigate whether fertilization failure after in vitro fertilization could be explained by polymorphisms in MT-ATP6 and MT-CYB genes. We performed a prospective comparative study of 111 fresh IVF cycles in Han Chinese between July 2011 and February 2013. Human sperm mitochondrial DNA (mtDNA) variants in the MT-CYB and MT-ATP6 genes were screened by polymerase chain reaction...
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