Article
Single nucleotide polymorphism rs527236194 of the cytochrome B gene (MT-CYB) is associated with alterations in sperm parameters.
Molecular biology reports - 1 Dec 2023
Gromenko Yulia Yu, Galimov Kamil S, Gilyazova Irina R, Galimova Elmira F, Bulygin Kirill V, Ryagin Sergey N, Galimov Shamil N, Litvitskiy Peter F, Piavchenko Gennadii A, Pavlov Valentin N
Abstract excerpt
BACKGROUND: The mitochondrial genome is substantially susceptible to mutations and has high polymorphism due to structural features, location, and lack of recombinant variability, as its inheritance is strictly maternal. All of these events can be accompanied by the accumulation of mitochondrial single nucleotide polymorphisms (mtSNPs) in the sperm. The aim of this research was to analyze the influence of...
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