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Article

βIV-Spectrin and CaMKII facilitate Kir6.2 regulation in pancreatic beta cells.

Proceedings of the National Academy of Sciences of the United States of America - 22 Oct 2013

Kline Crystal F, Wright Patrick J, Koval Olha M, Zmuda Erik J, Johnson Benjamin L, Anderson Mark E, Hai Tsonwin, Hund Thomas J, Mohler Peter J

Abstract excerpt

Identified over a dozen years ago in the brain and pancreatic islet, βIV-spectrin is critical for the local organization of protein complexes throughout the nervous system. βIV-Spectrin targets ion channels and adapter proteins to axon initial segments and nodes of Ranvier in neurons, and βIV-spectrin dysfunction underlies ataxia and early death in mice. Despite advances in βIV-spectrin research in the nervous...

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Identifiers

PMID: 24101510
DOI: 10.1073/pnas.1314195110
PMCID: PMC3808601

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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