Article
Leptospira interrogans serovar copenhageni harbors two lexA genes involved in SOS response.
PloS one - 1 Jan 2013
Fonseca Luciane S, da Silva Josefa B, Milanez Juliana S, Monteiro-Vitorello Claudia B, Momo Leonardo, de Morais Zenaide M, Vasconcellos Silvio A, Marques Marilis V, Ho Paulo L, da Costa Renata M A
Abstract excerpt
Bacteria activate a regulatory network in response to the challenges imposed by DNA damage to genetic material, known as the SOS response. This system is regulated by the RecA recombinase and by the transcriptional repressor lexA. Leptospira interrogans is a pathogen capable of surviving in the environment for weeks, being exposed to a great variety of stress agents and yet retaining its ability to infect the...
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