Constitutive SOS expression and damage‐inducible AddAB‐mediated recombinational repair systems for <i>Coxiella burnetii</i> as potential adaptations for survival within macrophages

Abstract excerpt

SUMMARY: Coxiella burnetii, a Gram-negative obligate intracellular pathogen, replicates within an parasitophorous vacuole with lysosomal characteristics. To understand how C. burnetii maintains genomic integrity in this environment, a database search for genes involved in DNA repair was performed. Major components of repair, SOS response and recombination were identified, including recA and ruvABC, but lexA and...

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