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Article

CIP2A Influences Survival in Colon Cancer and Is Critical for Maintaining Myc Expression

1 Oct 2013

Abstract excerpt

The cancerous inhibitor of protein phosphatase 2A (CIP2A) is an oncogenic factor that stabilises the c-Myc protein. CIP2A is overexpressed in several tumours, and expression levels are an independent marker for long-term outcome. To determine whether CIP2A expression is elevated in colon cancer and whether it might serve as a prognostic marker for survival, we analysed CIP2A mRNA expression by real-time PCR in...

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PMID: 24098375
DOI: 10.1371/journal.pone.0075292

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