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Overexpression of protein regulator of cytokinesis 1 facilitates tumor growth and indicates unfavorable prognosis of patients with colon cancer

31 Oct 2020

Abstract excerpt

BACKGROUND: Protein regulator of cytokinesis 1 (PRC1) has been reported to play important role in the pathogenesis of various cancers. However, its role in colon cancer has not been studied. Here, we aimed to investigate the biological functions and potential mechanism of PRC1 in colon cancer. METHODS: The expression level of PRC1 in colon cancer tissues and cell lines was detected by quantitative real-time...

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PMID: 33292244
DOI: 10.1186/s12935-020-01618-9

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