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Clinical profiles of Parkinson's disease associated with common leucine-rich repeat kinase 2 and glucocerebrosidase genetic variants in Chinese individuals.

Neurobiology of aging - 1 Mar 2014

Wang Chaodong, Cai Yanning, Gu Zhuqin, Ma Jinghong, Zheng Zheng, Tang Bei-Sha, Xu Yanming, Zhou Yongtao, Feng Tao, Wang Tao, Chen Sheng-Di, Chan Piu

Abstract excerpt

Clinical profiles of Parkinson's disease (PD) related to LRRK2 (LRRK2-PD), and GBA (GBA-PD) genes have not been reported in Chinese individuals. In this study, we have investigated motor and non-motor aspects in 1638 Chinese PD patients who carried LRRK2 G2385R or R1628P (LRRK2-PD, n = 223), GBA L444P variant (GBA-PD, n = 49), or none of the variants (idiopathic PD [IPD], n = 1366). As a result, age at onset and...

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PMID: 24095219
DOI: 10.1016/j.neurobiolaging.2013.08.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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