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Article

Neural and environmental factors impacting maternal behavior differences in high- versus low-novelty-seeking rats.

Hormones and behavior - 1 Apr 2010

Clinton Sarah M, Bedrosian Tracy A, Abraham Antony D, Watson Stanley J, Akil Huda

Abstract excerpt

Selective breeding of rats exhibiting differences in novelty-induced locomotion revealed that this trait predicts several differences in emotional behavior. Bred High Responders (bHRs) show exaggerated novelty-induced locomotion, aggression, and psychostimulant self-administration, compared to bred Low Responders (bLRs), which are inhibited and prone to anxiety- and depression-like behavior. Our breeding studies...

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Identifiers

PMID: 20156440
DOI: 10.1016/j.yhbeh.2010.02.004
PMCID: PMC2917072

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