Article
Functional characterization of the trypanosome translational repressor SCD6.
The Biochemical journal - 1 Jan 2014
Cristodero Marina, Schimanski Bernd, Heller Manfred, Roditi Isabel
Abstract excerpt
The storage of translationally inactive mRNAs in cytosolic granules enables cells to react flexibly to environmental changes. In eukaryotes, Scd6 (suppressor of clathrin deficiency 6)/Rap55 (RNA-associated protein 55), a member of the LSm14 (like-Sm14) family, is an important factor in the formation and activity of P-bodies, where mRNA decay factors accumulate, in stress granules that store mRNAs under adverse...
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