Article
Discovery of a splicing regulator required for cell cycle progression.
PLoS genetics - 1 Jan 2013
Suvorova Elena S, Croken Matthew, Kratzer Stella, Ting Li-Min, Conde de Felipe Magnolia, Balu Bharath, Markillie Meng L, Weiss Louis M, Kim Kami, White Michael W
Abstract excerpt
In the G1 phase of the cell division cycle, eukaryotic cells prepare many of the resources necessary for a new round of growth including renewal of the transcriptional and protein synthetic capacities and building the machinery for chromosome replication. The function of G1 has an early evolutionary origin and is preserved in single and multicellular organisms, although the regulatory mechanisms conducting G1...
Topics
- Alternative Splicing
- Cell Cycle
- Conserved Sequence
- G1 Phase
- Gene Expression Regulation
- Humans
- Mutation
- Nucleotide Motifs
- RNA, Messenger
- RNA-Binding Proteins
- Sequence Homology, Amino Acid
- Temperature
- Toxoplasma