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Article

Differentiation of mouse induced pluripotent stem cells (iPSCs) into nucleus pulposus-like cells in vitro.

PloS one - 1 Jan 2013

Chen Jun, Lee Esther J, Jing Liufang, Christoforou Nicolas, Leong Kam W, Setton Lori A

Abstract excerpt

A large percentage of the population may be expected to experience painful symptoms or disability associated with intervertebral disc (IVD) degeneration - a condition characterized by diminished integrity of tissue components. Great interest exists in the use of autologous or allogeneic cells delivered to the degenerated IVD to promote matrix regeneration. Induced pluripotent stem cells (iPSCs), derived from a...

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Identifiers

PMID: 24086564
DOI: 10.1371/journal.pone.0075548
PMCID: PMC3783442

Genes

IVD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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