Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Molecular phenotypes of notochordal cells purified from immature nucleus pulposus.

European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society - 1 Aug 2006

Chen Jun, Yan Wei, Setton Lori A

Abstract excerpt

The immature nucleus pulposus (NP) is populated by cells of notochordal-origin that are larger and contain an extensive cytoskeletal network and numerous vacuoles. The disappearance of these cells with age is believed important in regulating metabolic shifts that may contribute to age-related disc degeneration. The precise biological function of these notochordal cells in the immature NP remains unclear, however,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Size
Share to Collagen Type I

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HSP70 Heat-Shock Proteins

Share to Integrins

Share to Intervertebral Disc

Share to Notochord

Share to Proto-Oncogene Proteins c-fos

Share to Tissue Inhibitor of Metalloproteinase-1

Source

Open in PubMed Open full text

Identifiers

PMID: 16547755
DOI: 10.1007/s00586-006-0088-x
PMCID: PMC2335373

Genes

TIMP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Molecular phenotypes of notochordal cells purified from immature nucleus pulposus.PMID 16547755Read ↗

Notochordal and nucleus pulposus marker expression is maintained by sub-populations of adult human nucleus pulposus cells through aging and degenerationSemantic proximity Read ↗

Identifying molecular phenotype of nucleus pulposus cells in human intervertebral disc with aging and degeneration.Semantic proximity Read ↗

Same-species phenotypic comparison of notochordal and mature nucleus pulposus cells.Semantic proximity Read ↗

Human notochordal cell transcriptome unveils potential regulators of cell function in the developing intervertebral discSemantic proximity Read ↗

An understanding of intervertebral disc development, maturation and cell phenotype provides clues to direct cell-based tissue regeneration therapies for disc degeneration.Semantic proximity Read ↗

Toward an understanding of the role of notochordal cells in the adult intervertebral disc: From discord to accordSemantic proximity Read ↗

CD24 Positive Nucleus Pulposus Cells in Adult Human Intervertebral Discs Maintain a More Notochordal Phenotype Than GD2 Positive CellsSemantic proximity Read ↗

Notochordal Cell-Based Treatment Strategies and Their Potential in Intervertebral Disc RegenerationSemantic proximity Read ↗

Differentiation of intervertebral notochordal cells through live automated cell imaging system in vitro.Semantic proximity Read ↗

The Notochordal Cell in the Nucleus Pulposus: A Review in the Context of Tissue EngineeringSemantic proximity Read ↗

Differential expression level of cytokeratin 8 in cells of the bovine nucleus pulposus complicates the search for specific intervertebral disc cell markersSemantic proximity Read ↗

Loss of notochordal cell phenotype in 3D-cell cultures: implications for disc physiology and disc repair.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.