Article
HLA class I and class II conserved extended haplotypes and their fragments or blocks in Mexicans: implications for the study of genetic diversity in admixed populations.
PloS one - 1 Jan 2013
Zúñiga Joaquín, Yu Neng, Barquera Rodrigo, Alosco Sharon, Ohashi Marina, Lebedeva Tatiana, Acuña-Alonzo Víctor, Yunis María, Granados-Montiel Julio, Cruz-Lagunas Alfredo, Vargas-Alarcón Gilberto, Rodríguez-Reyna Tatiana S, Fernandez-Viña Marcelo, Granados Julio, Yunis Edmond J
Abstract excerpt
Major histocompatibility complex (MHC) genes are highly polymorphic and informative in disease association, transplantation, and population genetics studies with particular importance in the understanding of human population diversity and evolution. The aim of this study was to describe the HLA diversity in Mexican admixed individuals. We studied the polymorphism of MHC class I (HLA-A, -B, -C), and class II...
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