Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Strong Selection at MHC in Mexicans since Admixture

10 Feb 2016

Abstract excerpt

Mexicans are a recent admixture of Amerindians, Europeans, and Africans. We performed local ancestry analysis of Mexican samples from two genome-wide association studies obtained from dbGaP, and discovered that at the MHC region Mexicans have excessive African ancestral alleles compared to the rest of the genome, which is the hallmark of recent selection for admixed samples. The estimated selection coefficients...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood groups and transfusion
Share to Genetic and phenotypic traits in livestock
Share to Genetic Associations and Epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26863142
DOI: 10.1371/journal.pgen.1005847

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Strong Selection at MHC in Mexicans since AdmixturePMID 26863142Read ↗

Disentangling signatures of selection before and after European colonization in Latin AmericansSemantic proximity Read ↗

Disentangling Signatures of Selection Before and After European Colonization in Latin Americans.Semantic proximity Read ↗

Admixture-enabled selection for rapid adaptive evolution in the AmericasSemantic proximity Read ↗

Whole genome sequencing of 76 Mexican Indigenous reveals recent selection signatures linked to pathogens and diet adaptationSemantic proximity Read ↗

Population history and gene divergence in Native Mexicans inferred from 76 human exomesSemantic proximity Read ↗

Population History and Gene Divergence in Native Mexicans Inferred from 76 Human Exomes.Semantic proximity Read ↗

Dietary, Cultural, and Pathogens-Related Selective Pressures Shaped Differential Adaptive Evolution among Native Mexican Populations.Semantic proximity Read ↗

Demographic history and selection at HLA loci in Native Americans.Semantic proximity Read ↗

Genome-wide distribution of ancestry in Mexican Americans.Semantic proximity Read ↗

Dietary, Cultural and Pathogens-related Selective Pressures Shaped Differential Adaptive Evolution Among Native Mexican PopulationsSemantic proximity Read ↗

Detecting Selection in Multiple Populations by Modeling Ancestral Admixture Components.Semantic proximity Read ↗

The genomic signatures of natural selection in admixed human populationsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.