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Profiling the genetic diversity of the HLA system in Mexico using 9-locus allele and haplotype frequencies from donors in the NMDP Mexico donor center.

Human immunology - 1 Jul 2025

Madbouly Abeer, Bashyal Pradeep, Banos Andrea, Ramirez Jair, Whitaker Cameron, Fernandez-Vina Marcelo, Springer Brianna, Ybarra Yvonne, Maiers Martin, Bolon Yung-Tsi

Abstract excerpt

Profiling the HLA diversity at the population level benefits multiple clinical and anthropological applications, such as tracing population migration, identifying genetic relationships between different groups, quantifying the added diversity in a global donor pool and matching for solid organ and stem cell transplantation. We calculated nine-locus HLA-A ∼ C ∼ B ∼ DRB1 ∼ DRB3/4/5 ∼ DQA1 ∼ DQB1 ∼ DPA1 ∼ DPB1...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 40334347
DOI: 10.1016/j.humimm.2025.111324

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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