Article
Genetic variation in the hypothalamic pathways and its role on obesity.
Obesity reviews : an official journal of the International Association for the Study of Obesity - 1 Nov 2009
van Vliet-Ostaptchouk J V, Hofker M H, van der Schouw Y T, Wijmenga C, Onland-Moret N C
Abstract excerpt
Over recent decades, the prevalence of obesity has increased dramatically worldwide. Although this epidemic is mainly attributable to modern (western) lifestyle, multiple twin and adoption studies indicate the significant role of genes in the individual's predisposition to becoming obese. As the hypothalamus plays a central role in controlling body weight, its regulatory circuits may represent a crucial system in...
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