Article
Therapeutic strategies in male breast cancer: clinical implications of chromosome 17 gene alterations and molecular subtypes.
Breast (Edinburgh, Scotland) - 1 Dec 2013
Schildhaus Hans-Ulrich, Schroeder Lars, Merkelbach-Bruse Sabine, Binot Elke, Büttner Reinhard, Kuhn Walther, Rudlowski Christian
Abstract excerpt
Male breast cancer (MBC) is a rare disease. To date, therapy is mainly based on studies and clinical experiences with breast cancer in women. Only little is known about molecular typing of MBC, particularly with regard to potential biological predictors for adjuvant therapy. In female breast cancer tumors with chromosome 17 centromere (CEP17) duplication, HER2 and/or Topoisomerase II alpha (Topo II-α) gene...
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