Article
BRCA1 and BRCA2 mutations in males with familial breast and ovarian cancer syndrome. Results of a Spanish multicenter study.
Familial cancer - 1 Dec 2015
de Juan Inmaculada, Palanca Sarai, Domenech Asunción, Feliubadaló Lidia, Segura Ángel, Osorio Ana, Chirivella Isabel, de la Hoya Miguel, Sánchez Ana Beatriz, Infante Mar, Tena Isabel, Díez Orland, Garcia-Casado Zaida, Vega Ana, Teulé Àlex, Barroso Alicia, Pérez Pedro, Durán Mercedes, Carrasco Estela, Juan-Fita M José, Murria Rosa, Llop Marta, Barragan Eva, Izquierdo Ángel, Benítez Javier, Caldés Trinidad, Salas Dolores, Bolufer Pascual
Abstract excerpt
Male breast cancer (MBC) is a rare disease that represents <1% of all breast cancers (BCs). We analyze the results of a multicenter study performed in Spanish familial MBC including family history of hereditary breast and ovarian cancer syndrome (HBOCS) and clinicopathological features. We also study the relationship between BRCA1/BRCA2 mutational status in male relatives affected with cancer (MAC) and, family...
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