Article
Characterisation of male breast cancer: a descriptive biomarker study from a large patient series.
Scientific reports - 28 Mar 2017
Humphries Matthew P, Sundara Rajan Sreekumar, Honarpisheh Hedieh, Cserni Gabor, Dent Jo, Fulford Laura, Jordan Lee B, Jones J Louise, Kanthan Rani, Litwiniuk Maria, Di Benedetto Anna, Mottolese Marcella, Provenzano Elena, Shousha Sami, Stephens Mark, Kulka Janina, Ellis Ian O, Titloye Akinwale N, Hanby Andrew M, Shaaban Abeer M, Speirs Valerie
Abstract excerpt
Male breast cancer (MBC) is rare. We assembled 446 MBCs on tissue microarrays and assessed clinicopathological information, together with data from 15 published studies, totalling 1984 cases. By immunohistochemistry we investigated 14 biomarkers (ERα, ERβ1, ERβ2, ERβ5, PR, AR, Bcl-2, HER2, p53, E-cadherin, Ki67, survivin, prolactin, FOXA1) for survival impact. The main histological subtype in our cohort and...
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