The important molecular markers on chromosome 17 and their clinical impact in breast cancer.

doi:10.3390/ijms12095672

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Article

The important molecular markers on chromosome 17 and their clinical impact in breast cancer.

International journal of molecular sciences - 1 Jan 2011

Zhang Wei, Yu Yingyan

Abstract excerpt

Abnormalities of chromosome 17 are important molecular genetic events in human breast cancers. Several famous oncogenes (HER2, TOP2A and TAU), tumor suppressor genes (p53, BRCA1 and HIC-1) or DNA double-strand break repair gene (RDM1) are located on chromosome 17. We searched the literature on HER2, TOP2A, TAU, RDM1, p53, BRCA1 and HIC-1 on the Pubmed database. The association of genes with chromosome 17,...

Topics

Antineoplastic Agents
Biomarkers, Tumor
Breast Neoplasms
Chromosome Aberrations
Chromosomes, Human, Pair 17
Female
Gene Expression Regulation, Neoplastic
Genetic Predisposition to Disease
Humans

Source

Open in PubMed Open full text

Identifiers

PMID: 22016618
DOI: 10.3390/ijms12095672
PMCID: PMC3189742

Genes

BRCA1
RDM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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