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Article

Mutagenesis by proximity to the recA gene of Escherichia coli.

Journal of molecular biology - 20 Jan 1990

Liu S K, Tessman I

Abstract excerpt

Escherichia coli recA (Prtc) strains, which produce protease constitutive RecA proteins in the absence of DNA-damaging treatments, display an increased frequency of spontaneous mutations. These mutations occurred preferentially in the neighborhood of the recA gene. This cis-like mutagenic effect was observed in the recA, rexAB, phoE and bio genes. The localized mutagenesis can be explained by the ease with which...

Topics

Chromosome Mapping
Chromosomes, Bacterial
Escherichia coli
Genes, Bacterial
Genes, Regulator
Genotype
Mutation
Phenotype
Plasmids
Rec A Recombinases

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 2407851
DOI: 10.1016/0022-2836(90)90356-Q

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2407851-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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