Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Biochemical and structural aspects of the ATP‐binding domain in inflammasome‐forming human NLRP proteins

23 Sept 2013

Abstract excerpt

Nucleotide-binding domain and leucine-rich repeat-containing receptors (NLRs) regulate innate immunity by activating inflammatory responses in a variety of biological systems following the recognition of pathogen- or disease-associated molecular patterns. NLRs are characterized by a central nucleotide-binding and oligomerization (NACHT) domain found in P-loop NTPases. In this review, we detail the functional and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cholesterol and Lipid Metabolism
Share to Inflammasome and immune disorders
Share to interferon and immune responses

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24078393
DOI: 10.1002/iub.1210

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Biochemical and structural aspects of the ATP‐binding domain in inflammasome‐forming human NLRP proteinsPMID 24078393Read ↗

Regulation and Function of the Nucleotide Binding Domain Leucine-Rich Repeat-Containing Receptor, Pyrin Domain-Containing-3 Inflammasome in Lung DiseaseSemantic proximity Read ↗

Identification of Multifaceted Binding Modes for Pyrin and ASC Pyrin Domains Gives Insights into Pyrin Inflammasome AssemblySemantic proximity Read ↗

The role of NLRP12 in inflammatory diseasesSemantic proximity Read ↗

Posttranslational modifications of NLRP3 and their regulatory roles in inflammasome activationSemantic proximity Read ↗

The inflammasome in pathogen recognition and inflammationSemantic proximity Read ↗

Bypassing PELO-mediated ATPase activation of NLR is a common pathogenic cause of <i>NLR</i> -associated autoinflammatory diseasesSemantic proximity Read ↗

Recent Insights in Pyrin Inflammasome Activation: Identifying Potential Novel Therapeutic Approaches in Pyrin-Associated Autoinflammatory SyndromesSemantic proximity Read ↗

The NLRP1 inflammasome: new mechanistic insights and unresolved mysteriesSemantic proximity Read ↗

Inflammasomes: mechanism of action, role in disease, and therapeuticsSemantic proximity Read ↗

The Nod-Like Receptor (NLR) Family: A Tale of Similarities and DifferencesSemantic proximity Read ↗

Human NLRP1: From the shadows to center stageSemantic proximity Read ↗

Regulation and Sensing of Inflammasomes and Their Impact on Intestinal HealthSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.