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The Nod-Like Receptor (NLR) Family: A Tale of Similarities and Differences

29 Apr 2008

Abstract excerpt

Innate immunity represents an important system with a variety of vital processes at the core of many diseases. In recent years, the central role of the Nod-like receptor (NLR) protein family became increasingly appreciated in innate immune responses. NLRs are classified as part of the signal transduction ATPases with numerous domains (STAND) clade within the AAA+ ATPase family. They typically feature an...

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PMID: 18446235
DOI: 10.1371/journal.pone.0002119

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