Article
IL-4 gene polymorphisms and their association with atopic asthma and allergic rhinitis in Pakistani patients.
Journal of investigational allergology & clinical immunology - 1 Jan 2013
Micheal S, Minhas K, Ishaque M, Ahmed F, Ahmed A
Abstract excerpt
BACKGROUND AND OBJECTIVE: Interleukin (IL) 4 is a cytokine that mediates allergic responses. Different single nucleotide polymorphisms (SNPs) can influence the immune response mediated by cytokines. The aim of the present study was to investigate the possible association between IL-4 polymorphisms and allergic rhinitis and atopic asthma. METHODS: A total of 214 atopic patients (108 with asthma and 106 with...
Topics
- Asian People
- Asthma
- Case-Control Studies
- Gene Frequency
- Genetic Predisposition to Disease
- Genotype
- Humans
- Interleukin-4
- Pakistan
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
