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Article

Importance of common TLR2 genetic variants on clinical phenotypes and risk in tuberculosis disease in a Western Chinese population.

Infection, genetics and evolution : journal of molecular epidemiology and evolutionary genetics in infectious diseases - 1 Jun 2018

Zhang Jingwei, Zhao Zhenzhen, Zhong Huiyu, Wu Lijuan, Zhou Wenjing, Peng Wu, Hu Xuejiao, Song Jiajia, Liu Tangyuheng, Wu Qian, Bai Hao, Zhou Yi, Chen Xuerong, Chen Jie, Lu Xiaojun, Ying Binwu

Abstract excerpt

OBJECTIVES: Abundant studies have suggested that TLR2 genetic variants involve in susceptibility to TB infection. We tried to verified the hypothesis that TLR2 genetic loci effect on the susceptibility to TB in the Western Chinese population. METHODS: A total 1109 individuals (634 TB patients and 475 healthy controls) were genotyped for rs3804099, rs3804100 and rs76112010 by using a custom-by-design 2x48-Plex SNP...

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PMID: 29486365
DOI: 10.1016/j.meegid.2018.02.031

Genes

TLR2

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