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Article

Tissue-specific differences in the regulation of KIBRA gene expression involve transcription factor TCF7L2 and a complex alternative promoter system.

Journal of molecular medicine (Berlin, Germany) - 1 Feb 2014

Guske Katrin, Schmitz Boris, Schelleckes Michael, Duning Kerstin, Kremerskothen Joachim, Pavenstädt Hermann J, Brand Stefan-Martin, Brand Eva

Abstract excerpt

UNLABELLED: KIBRA has been described as a key regulator of the Hippo signaling pathway, regulating organ size control, cell contact inhibition, cell growth, as well as tumorigenesis and cystogenesis. Since there is scarce information on KIBRA gene expression regulation, we analyzed the molecular basis of tissue-specific KIBRA expression in human kidney epithelial (IHKE, HPCT) and neuroblastoma (SH-SY5Y, SK-SN-SH)...

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PMID: 24072042
DOI: 10.1007/s00109-013-1089-y

Genes

YAP1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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