Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phospho‐ΔNp63α regulates <i>AQP3, ALOX12B, CASP14</i> and <i>CLDN1</i> expression through transcription and microRNA modulation

23 Sept 2013

Abstract excerpt

Cisplatin-induced and ATM-phosphorylated (p)-ΔNp63α regulates the expression of epidermal differentiation and skin barrier regulators (AQP3, CASP14, ALOX12B, and CLDN1) in squamous cell carcinoma (SCC) cells by dual transcriptional and post-transcriptional mechanisms. We found that p-ΔNp63α bound to target gene promoters, and regulated the activity of the tested promoters in vitro. P-ΔNp63α was shown to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer-related Molecular Pathways
Share to RNA Interference and Gene Delivery
Share to RNA Research and Splicing

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 24070899
DOI: 10.1016/j.febslet.2013.09.023

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phospho‐ΔNp63α regulates <i>AQP3, ALOX12B, CASP14</i> and <i>CLDN1</i> expression through transcription and microRNA modulationPMID 24070899Read ↗

Phospho-ΔNp63α/miR-885-3p axis in tumor cell life and cell death upon cisplatin exposureSemantic proximity Read ↗

Phospho-ΔNp63α-dependent regulation of autophagic signaling through transcription and micro-RNA modulationSemantic proximity Read ↗

Global tumor protein p53/p63 interactomeSemantic proximity Read ↗

Phospho-ΔNp63α-dependent microRNAs modulate chemoresistance of squamous cell carcinoma cells to cisplatin: at the crossroads of cell life and death.Semantic proximity Read ↗

ΔNp63 in squamous cell carcinoma: defining the oncogenic routes affecting epigenetic landscape and tumour microenvironmentSemantic proximity Read ↗

Induced multipotency in adult keratinocytes through down-regulation of <i>ΔNp63</i> or <i>DGCR8</i>Semantic proximity Read ↗

Phospho-ΔNp63α/Rpn13-dependent regulation of LKB1 degradation modulates autophagy in cancer cellsSemantic proximity Read ↗

Phospho-DeltaNp63alpha/NF-Y protein complex transcriptionally regulates DDIT3 expression in squamous cell carcinoma cells upon cisplatin exposure.Semantic proximity Read ↗

Intersection of the p63 and NF‐κB pathways in epithelial homeostasis and diseaseSemantic proximity Read ↗

ΔNp63α Confers Tumor Cell Resistance to Cisplatin through the AKT1 Transcriptional RegulationSemantic proximity Read ↗

ΔNp63 activates the Fanconi anemia DNA repair pathway and limits the efficacy of cisplatin treatment in squamous cell carcinomaSemantic proximity Read ↗

ERK3 is transcriptionally upregulated by ∆Np63α and mediates the role of ∆Np63α in suppressing cell migration in Non-Melanoma Skin CancersSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.