Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Phospho-ΔNp63α-dependent microRNAs modulate chemoresistance of squamous cell carcinoma cells to cisplatin: at the crossroads of cell life and death.

FEBS letters - 19 Aug 2013

Ratovitski Edward A

Abstract excerpt

The tumor protein p63/microRNA functional network appears to play a decisive role in chemoresistance of human epithelial cancers. The cisplatin- and phosphorylated-ΔNp63α-dependent microRNAs, whose expression was varied in sensitive and resistant squamous cell carcinoma cells (SCC, which were derived from larynx and tongue tumors), were shown to modulate the expression of multiple members of cell cycle arrest,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Ataxia Telangiectasia Mutated Proteins
Share to Autophagy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Carcinoma, Squamous Cell

Share to Cell Cycle

Share to Cisplatin

Share to Head and Neck Neoplasms

Share to Neoplasms, Glandular and Epithelial

Share to Tumor Suppressor Proteins

Source

Identifiers

PMID: 23831023
DOI: 10.1016/j.febslet.2013.06.020

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Phospho-ΔNp63α-dependent microRNAs modulate chemoresistance of squamous cell carcinoma cells to cisplatin: at the crossroads of cell life and death.PMID 23831023Read ↗

Phospho-ΔNp63α-dependent regulation of autophagic signaling through transcription and micro-RNA modulationSemantic proximity Read ↗

Global tumor protein p53/p63 interactomeSemantic proximity Read ↗

Phospho-ΔNp63α/miR-885-3p axis in tumor cell life and cell death upon cisplatin exposureSemantic proximity Read ↗

ΔNp63α Confers Tumor Cell Resistance to Cisplatin through the AKT1 Transcriptional RegulationSemantic proximity Read ↗

A microRNA-dependent program controls p53-independent survival and chemosensitivity in human and murine squamous cell carcinomaSemantic proximity Read ↗

A microRNA-dependent circuit controlling p63/p73 homeostasis: p53 family cross-talk meets therapeutic opportunitySemantic proximity Read ↗

Phospho-ΔNp63α/Rpn13-dependent regulation of LKB1 degradation modulates autophagy in cancer cellsSemantic proximity Read ↗

Interplay of p62-mTORC1 and EGFR signaling promotes cisplatin resistance in oral cancerSemantic proximity Read ↗

Phospho‐ΔNp63α regulates <i>AQP3, ALOX12B, CASP14</i> and <i>CLDN1</i> expression through transcription and microRNA modulationSemantic proximity Read ↗

MicroRNA profiling of cisplatin-resistant oral squamous cell carcinoma cell lines enriched with cancer-stem-cell-like and epithelial-mesenchymal transition-type features.Semantic proximity Read ↗

ΔNp63 activates the Fanconi anemia DNA repair pathway and limits the efficacy of cisplatin treatment in squamous cell carcinomaSemantic proximity Read ↗

Identification of cisplatin-resistance related genes in head and neck squamous cell carcinoma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.