Article
Aminopeptidase N (CD13) is involved in phagocytic processes in human dendritic cells and macrophages.
BioMed research international - 1 Jan 2013
Villaseñor-Cardoso Mónica I, Frausto-Del-Río Dulce A, Ortega Enrique
Abstract excerpt
Aminopeptidase N (APN or CD13) is a membrane ectopeptidase expressed by many cell types, including myelomonocytic lineage cells: monocytes, macrophages, and dendritic cells. CD13 is known to regulate the biological activity of various peptides by proteolysis, and it has been proposed that CD13 also participates in several functions such as angiogenesis, cell adhesion, metastasis, and tumor invasion. We had...
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