Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Analysis of clathrin light chain-heavy chain interactions using truncated mutants of rat liver light chain LCB3.

The Journal of biological chemistry - 5 Mar 1990

Scarmato P, Kirchhausen T

Abstract excerpt

Clathrin light chains are extended molecules located along the proximal segment of each of the three heavy chain legs of a clathrin trimer. All mammalian light chains share a central segment with 10 repeated heptad motifs believed to mediate the interaction with clathrin heavy chains. In order to test this model in more detail, we have expressed intact rat liver clathrin light chain LCB3 in Escherichia coli and...

Topics

Animals
Base Sequence
Cattle
Chromosome Deletion
Clathrin
Cloning, Molecular
DNA
DNA, Recombinant
Escherichia coli
Liver
Macromolecular Substances
Molecular Sequence Data

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Mutation

Oligonucleotide Probes

Plasmids

Protein Binding

Rats

Source

Identifiers

PMID: 2406259

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-2406259-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 8 closest

Analysis of clathrin light chain-heavy chain interactions using truncated mutants of rat liver light chain LCB3.PMID 2406259Read ↗

Yeast clathrin has a distinctive light chain that is important for cell growth.Semantic proximity Read ↗

Contribution of cysteines to clathrin trimerization domain stability and mapping of light chain binding.Semantic proximity Read ↗

Huntingtin-interacting protein 1 (Hip1) and Hip1-related protein (Hip1R) bind the conserved sequence of clathrin light chains and thereby influence clathrin assembly in vitro and actin distribution in vivo.Semantic proximity Read ↗

Sequence of the clathrin heavy chain from Saccharomyces cerevisiae and requirement of the COOH terminus for clathrin function.Semantic proximity Read ↗

Compromise of clathrin function and membrane association by clathrin light chain deletion.Semantic proximity Read ↗

Prokaryotic expression of bovine lactoferrin deletion mutants that bind to the Ca2+-dependent lactoferrin receptor on isolated rat hepatocytes.Semantic proximity Read ↗

Identification of a novel interaction site between the large hepatitis delta antigen and clathrin that regulates the assembly of genotype III hepatitis delta virus.Semantic proximity Read ↗

Structural requirements for interactions between leucine-sorting signals and clathrin-associated adaptor protein complex AP3.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.