Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A mutation in the FHA domain of Coprinus cinereus Nbs1 Leads to Spo11-independent meiotic recombination and chromosome segregation.

G3 (Bethesda, Md.) - 6 Nov 2013

Crown K Nicole, Savytskyy Oleksandr P, Malik Shehre-Banoo, Logsdon John, Williams R Scott, Tainer John A, Zolan Miriam E

Abstract excerpt

Nbs1, a core component of the Mre11-Rad50-Nbs1 complex, plays an essential role in the cellular response to DNA double-strand breaks (DSBs) and poorly understood roles in meiosis. We used the basidiomycete Coprinus cinereus to examine the meiotic roles of Nbs1. We identified the C. cinereus nbs1 gene and demonstrated that it corresponds to a complementation group previously known as rad3. One allele, nbs1-2,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromosome Segregation
Share to Chromosomes

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to DNA Breaks, Double-Stranded

Share to Endodeoxyribonucleases

Share to Fungal Proteins

Share to Histones

Share to Meiosis

Share to Spores, Fungal

Source

Open in PubMed Open full text

Identifiers

PMID: 24062528
DOI: 10.1534/g3.113.007906
PMCID: PMC3815056

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A mutation in the FHA domain of Coprinus cinereus Nbs1 Leads to Spo11-independent meiotic recombination and chromosome segregation.PMID 24062528Read ↗

Pathway analysis of radiation-sensitive meiotic mutants of Coprinus cinereus.Semantic proximity Read ↗

Identification of DSB-1, a protein required for initiation of meiotic recombination in Caenorhabditis elegans, illuminates a crossover assurance checkpoint.Semantic proximity Read ↗

Coprinus cinereus rad50 mutants reveal an essential structural role for Rad50 in axial element and synaptonemal complex formation, homolog pairing and meiotic recombination.Semantic proximity Read ↗

Interdependent and separable functions of <i>C. elegans</i> MRN-C complex members couple formation and repair of meiotic DSBsSemantic proximity Read ↗

Meiotic localization of Mre11 and Rad50 in wild type, spo11-1, and MRN complex mutants of Coprinus cinereus.Semantic proximity Read ↗

Chromosome dynamics in rad12 mutants of Coprinus cinereus.Semantic proximity Read ↗

Meiotic recombination in C. elegans initiates by a conserved mechanism and is dispensable for homologous chromosome synapsis.Semantic proximity Read ↗

SID1-1: a mutation affecting meiotic sister-chromatid association in yeast.Semantic proximity Read ↗

Mutations in Saccharomyces cerevisiae that block meiotic prophase chromosome metabolism and confer cell cycle arrest at pachytene identify two new meiosis-specific genes SAE1 and SAE3.Semantic proximity Read ↗

A high throughput genetic screen identifies new early meiotic recombination functions in Arabidopsis thaliana.Semantic proximity Read ↗

Nbs1 is essential for DNA repair by homologous recombination in higher vertebrate cells.Semantic proximity Read ↗

High throughput sequencing reveals alterations in the recombination signatures with diminishing Spo11 activity.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.