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Article

Wt1 negatively regulates beta-catenin signaling during testis development.

Development (Cambridge, England) - 1 May 2008

Chang Hao, Gao Fei, Guillou Florian, Taketo Makoto M, Huff Vicki, Behringer Richard R

Abstract excerpt

beta-Catenin, as an important effector of the canonical Wnt signaling pathway and as a regulator of cell adhesion, has been demonstrated to be involved in multiple developmental processes and tumorigenesis. beta-Catenin expression was found mainly on the Sertoli cell membrane starting from embryonic day 15.5 in the developing testes. However, its potential role in Sertoli cells during testis formation has not...

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Identifiers

PMID: 18403409
DOI: 10.1242/dev.018572
PMCID: PMC4038296

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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