Article
The TCF7L2 rs7903146 (T) allele is associated with type 2 diabetes in urban Ghana: a hospital-based case-control study.
BMC medical genetics - 23 Sept 2013
Danquah Ina, Othmer Till, Frank Laura K, Bedu-Addo George, Schulze Matthias B, Mockenhaupt Frank P
Abstract excerpt
BACKGROUND: Type 2 diabetes mellitus is increasing dramatically in sub-Saharan Africa, and genetic predisposition is likely involved in that. Yet, genetic variants known to confer increased susceptibility among Caucasians are far from being established in African populations. In Ghanaian adults, we examined associations of several of these polymorphisms with type 2 diabetes. METHODS: A hospital-based case-control...
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