Article
Common variants of the TCF7L2 gene are associated with increased risk of type 2 diabetes mellitus in a UK-resident South Asian population.
BMC medical genetics - 21 Feb 2008
Rees Simon D, Bellary Srikanth, Britten Abigail C, O'Hare J Paul, Kumar Sudhesh, Barnett Anthony H, Kelly M Ann
Abstract excerpt
BACKGROUND: Recent studies have implicated variants of the transcription factor 7-like 2 (TCF7L2) gene in genetic susceptibility to type 2 diabetes mellitus in several different populations. The aim of this study was to determine whether variants of this gene are also risk factors for type 2 diabetes development in a UK-resident South Asian cohort of Punjabi ancestry. METHODS: We genotyped four single nucleotide...
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