Article
Association between TCF7L2 polymorphism and type 2 diabetes mellitus susceptibility: a case-control study among the Bangladeshi population.
Molecular biology reports - 1 Jan 2023
Salauddin Asma, Chakma Kallyan, Hasan Md Mahbub, Akter Farhana, Chowdhury Nowshad Asgar, Chowdhury Sumon Rahman, Mannan Adnan
Abstract excerpt
BACKGROUND: Diabetes is a severe health burden for Bangladesh. Genetic polymorphism has been reported to be one of the major risk factors for diabetes in various studies. TCF7L2 (transcription factor 7 like 2) transcripts in the human β-cell have effects on β-cell survival, function, and Wnt signaling activation. This study aimed to evaluate the frequency and association of various polymorphisms namely TCF7L2...
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