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Article

Role of hypoxia and HIF2α in development of the sympathoadrenal cell lineage and chromaffin cell tumors with distinct catecholamine phenotypic features.

Advances in pharmacology (San Diego, Calif.) - 1 Jan 2013

Richter Susan, Qin Nan, Pacak Karel, Eisenhofer Graeme

Abstract excerpt

Hypoxia has wide-ranging impact in normal physiology and disease processes. This stimulus evokes changes in gene expression mediated by transcription factors termed hypoxia-inducible factors (HIFs) that affect numerous processes: angiogenesis, cell survival, cellular metabolism, stem cell self-renewal and multipotency, migration, invasiveness, and metastatic progression in tumor cells. Over the past decade,...

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Identifiers

PMID: 24054150
DOI: 10.1016/B978-0-12-411512-5.00014-2
PMCID: PMC3785008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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