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Multi-omics analysis based on integrated genomics, epigenomics and transcriptomics in pancreatic cancer.

Epigenomics - 1 Mar 2020

Kong Lingming, Liu Peng, Zheng Mingjun, Xue Busheng, Liang Keke, Tan Xiaodong

Abstract excerpt

Aim: Integrated analysis of genomics, epigenomics, transcriptomics and clinical information contributes to identify specific molecular subgroups and find novel biomarkers for pancreatic cancer. Materials & methods: The DNA copy number variation, the simple nucleotide variation, methylation and mRNA data of pancreatic cancer patients were obtained from The Cancer Genome Atlas. Four molecular subgroups (iC1, iC2,...

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PMID: 32048534
DOI: 10.2217/epi-2019-0374

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