Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Lynch syndrome: a pediatric perspective.

Journal of pediatric gastroenterology and nutrition - 1 Feb 2014

Huang Sherry C, Durno Carol A, Erdman Steven H

Abstract excerpt

Colorectal cancer is a rare disease in the pediatric age group and, when present, suggests an underlying genetic predisposition. The most common hereditary colon cancer susceptibility condition, Lynch syndrome (LS), previously known as hereditary nonpolyposis colorectal cancer, is an autosomal dominant condition caused by a germline mutation in 1 of 4 DNA mismatch repair (MMR) genes: MLH1, MSH2, MSH6, or PMS2....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Colorectal Neoplasms
Share to Colorectal Neoplasms, Hereditary Nonpolyposis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Mismatch Repair

Share to MSH6 gene

Share to PMS2 gene

Share to Germ-Line Mutation

Share to Pediatrics

Source

Identifiers

PMID: 24051481
DOI: 10.1097/MPG.0000000000000179

Genes

MLH1
MSH2
MSH6
PMS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lynch syndrome: a pediatric perspective.PMID 24051481Read ↗

Lynch syndrome: further defining the pediatric spectrum.Semantic proximity Read ↗

Clinical and molecular characteristics of constitutional mismatch repair deficiency syndrome: a case series of five children and appraisal of diagnostic guidelines.Semantic proximity Read ↗

Review: Clinical aspects of hereditary DNA Mismatch repair gene mutations.Semantic proximity Read ↗

Lynch Syndrome and Early-Onset Colorectal Cancer in Pediatric PatientsSemantic proximity Read ↗

Lynch syndrome and colorectal cancer: A review of current perspectives in molecular genetics and clinical strategiesSemantic proximity Read ↗

Lynch syndrome in the 21st century: clinical perspectives.Semantic proximity Read ↗

New Insights into Lynch Syndrome: A Narrative Review.Semantic proximity Read ↗

Pediatric Lynch syndrome: Clinical, genotypic, and left-sided patterns of colorectal cancer.Semantic proximity Read ↗

Current clinical topics of Lynch syndrome.Semantic proximity Read ↗

Review article: the Lynch syndrome (hereditary nonpolyposis colorectal cancer)*Semantic proximity Read ↗

Childhood cancers in families with and without Lynch syndrome.Semantic proximity Read ↗

Clinical and molecular features of pediatric cancer patients with Lynch syndromeSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.