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Article

Pediatric Lynch syndrome: Clinical, genotypic, and left-sided patterns of colorectal cancer.

Journal of pediatric gastroenterology and nutrition - 1 Jul 2026

Phen Claudia, Rojas Isabel, Friesen Hunter J, Swaggart Keri, Flahive Colleen B, MacFarland Suzanne P, Attard Thomas

Abstract excerpt

OBJECTIVES: To characterize the clinical, histopathologic, and molecular-genetic characteristics of Lynch syndrome (LS)-associated gastrointestinal disease in the pediatric population. METHODS: We conducted a scoping review, systematically searching PubMed and Embase® (from inception to October 16, 2025) and using controlled vocabulary and keywords, with additional screening of reference lists and conference...

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Topics

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Colorectal Neoplasms

Share to Colorectal Neoplasms, Hereditary Nonpolyposis

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Source

Identifiers

PMID: 42010922
DOI: 10.1002/jpn3.70445

Genes

MLH1
MSH2
MSH6
PMS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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Semantic proximity does not establish scientific evidence.

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