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Article

Methylenetetrahydrofolate reductase gene polymorphism and serum homocysteine levels in nonalcoholic fatty liver disease.

Annals of nutrition & metabolism - 1 Jan 2013

Franco Brochado Maria José, Domenici Fernanda Aparecida, Candolo Martinelli Ana de Lourdes, Zucoloto Sergio, de Carvalho da Cunha Selma Freire, Vannucchi Helio

Abstract excerpt

BACKGROUND/AIMS: Nonalcoholic fatty liver disease (NAFLD) is a metabolic disorder characterized by hepatic fat accumulation in the absence of alcohol consumption. Hyperhomocysteinemia is considered an independent risk factor for liver diseases, and the genetic polymorphisms C677T and A1298C in the MTHFR gene have been linked to hyperhomocysteinemia. The purpose of this study was to investigate serum homocysteine...

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Identifiers

PMID: 24051448
DOI: 10.1159/000353139

Genes

MTHFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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